AI Global Summit

L’AI applicata alla voce apre nuove possibilità per il monitoraggio non invasivo della salute dei pazienti. Attraverso l’analisi automatica dei segnali vocali, è possibile individuare precocemente alterazioni legate a disturbi respiratori, neurologici o vocali. Questo approccio offre nuove soluzioni di diagnosi e monitoraggio, capaci di raggiungere ampie popolazioni e integrabili nei percorsi clinici e domiciliari.

The quest to extend human healthspan and decode the biological mechanisms of aging is undergoing a profound transformation, driven by an inflection point in artificial intelligence. We are transitioning from a slow, observational approach in longevity science to a highly predictive, generative paradigm. I will explore how the convergence of advanced AI architectures and massive biological datasets is not just accelerating discovery, but fundamentally altering our approach to aging, cellular senescence, and age-related disease. At the foundation of this revolution are groundbreaking advances in biomolecular modeling and structural prediction. When coupled with emerging, purpose-built foundation models for biology and medicine, researchers are gaining the ability to decode intricate epigenetic and proteomic signatures. This enables the rational design of novel geroprotectors, targeted therapeutics, and highly personalized interventions with unprecedented speed and precision. However, the next frontier in longevity medicine lies in the transition from static structural mapping to dynamic biological simulation. The development of "world models" for biology and fully realized "virtual cells" represents a paradigm shift for the field. By simulating complex cellular behaviors and tissue-level interactions in silico, these dynamic models allow us to safely and rapidly test millions of potential anti-aging interventions. They enable researchers to predict complex systemic responses, model the long-term cascade of cellular aging, and evaluate multi-drug regimens without the immediate need for decades-long clinical trials.

In this keynote, Roberto Ascione explores the evolution of a vision that, over three decades, has helped transform digital health as we know it today. Drawing on the ideas presented in his book “The Future of Health”, he unpacks how the belief that digital technology could make care more accessible, sustainable, and human became a roadmap for innovation. With AI now accelerating every dimension of healthcare, from clinical decision support to patient engagement, from drug discovery to digital therapeutics, the keynote offers a clear perspective on how this transformation has taken shape over time. He shares lessons on which visionary ideas endured, how course corrections proved necessary, and why the most human ambitions, such as empowering patients, restoring the doctor patient relationship, and democratizing access, have proven the most durable. This is not a keynote about what’s coming. It’s the story of what has already arrived and what it took to get here.

Con il rilascio di ChatGPT e di altre piattaforme di intelligenza artificiale generativa, sempre più persone si rivolgono a questi sistemi per ottenere risposte riguardo alla propria salute. Questo fenomeno è destinato ad aumentare con il rilascio di strumenti come ChatGPT Salute. Tuttavia, le evidenze scientifiche suggeriscono che è importante usare queste tecnologie con cautela e solo in contesti specifici e controllati. L’intervento si propone di fare chiarezza su questi aspetti.

La digital health sta crescendo rapidamente, ma invece di semplificare l’accesso alle cure, ha spesso aumentato frammentazione e complessità. L'Ai Health rischia di amplificare questo caos se non si risolve il problema alla base: la mancanza di integrazione e di un linguaggio comprensibile tra servizi e attori del sistema sanitario. Questo intervento esplora l’evoluzione dalla digital health all’AI health, evidenziandone limiti e opportunità. Attraverso il caso Salute360, vedremo come unificare servizi, professionisti e pazienti in un’unica esperienza accessibile e continua.